Palmitoyl Dipeptide-5 Diaminohydroxybutyrate

Good

Peptide

Palmitoyl Dipeptide-5 Diaminohydroxybutyrate at a glance

  • Synthetic peptide
  • Derived partly from palmitic acid
  • Skin conditioning ingredient
  • Could also improve skin firmness

Palmitoyl Dipeptide-5 Diaminohydroxybutyrate description

Palmitoyl dipeptide-5 diaminohydroxybutyrate is a synthetic peptide creation from a reaction of the fatty acid palmitic and the amino acid derivative diaminohydroxybutyric acid with dipeptide-5. In cosmetics, its primary function is as a skin conditioning ingredient. This peptide is featured as part of an ingredient blend called SYN®-TACKS CB that also includes water, glycerin, and palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine. Manufacturers of the blend claim it improves skin elasticity, firmness, and suppleness by strengthening the junction between the dermis and the epidermis. In peptide blends, palmitoyl dipeptide-5 diaminohydroxybutyrate is generally used in amounts between 1-3%.

Palmitoyl Dipeptide-5 Diaminohydroxybutyrate references

  • SpecialChem, Website, Accessed October 2025
  • UL Prospector, Website, Accessed October 2025
  • National Institutes of Health, Website, Accessed October 2025
  • Journal of Biomaterials & Functional Materials, April 2025, ePublication

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings

Best

Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.

Good

Necessary to improve a formula's texture, stability, or penetration.

Average

Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.

Bad

There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.

Worst

May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.

unknown

We couldn't find this in our ingredient dictionary. We log all missing ingredients and make continuous updates.

Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.